What Causes Arthritis ?
With aging, the water content of the cartilage increases and its protein composition degenerates. Eventually, cartilage begins to degenerate by chipping or forming tiny cracks. In advanced cases, there is a total loss of the cartilage cushion between joint surfaces, which causes friction between the bones, leading to pain and restriction of joint mobility. This degeneration can also stimulate new bone outgrowths (spurs) to form around the joints. Osteoarthritis is sometimes found in several members of the same family, implying a heredity (genetic) basis for the disease.
Secondary osteoarthritis is caused by another disease or condition. Conditions that can cause secondary osteoarthritis include abnormal joints at birth (congenital abnormalities), diabetes and other hormone disorders, gout, obesity, repeated trauma or surgery to the joint structures.